dc.contributor.author | Güzel, Eda Çelik | |
dc.contributor.author | Çelik, Cem | |
dc.contributor.author | Abalı, Remzi | |
dc.contributor.author | Küçükyalçın, Volkan | |
dc.contributor.author | Çelik, Elcin | |
dc.contributor.author | Güzel, Murat | |
dc.contributor.author | Yılmaz, Murat | |
dc.date.accessioned | 2022-05-11T14:10:12Z | |
dc.date.available | 2022-05-11T14:10:12Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 0951-3590 | |
dc.identifier.issn | 1473-0766 | |
dc.identifier.uri | https://doi.org/10.3109/09513590.2014.888412 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5322 | |
dc.description.abstract | We aimed to investigate whether overweight/obesity is associated with omentin and chemerin. The study group consisted of 81 women with Polycystic ovarian syndrome (PCOS) (41 lean, BMI<25 kg/m(2) and 40 overweight or obese, BMI>25 kg/m(2)) and 61 healthy subjects (31 lean, BMI<25 kg/m(2) and 30 overweight or obese, BMI>25 kg/m(2); control group). The clinical, endocrine, metabolic parameters, plasma omentin and chemerin levels were measured in patients and compared to control. In all subjects with PCOS (n = 80), serum chemerin levels were higher compared with those of the controls (n = 58) (7.71 +/- 1.78 ng/mL versus 6.94 +/- 0.82 ng/mL, p = 0.003). However, serum omentin levels were not significantly different between the PCOS subjects and the controls (1.55 +/- 0.43 ng/mL versus 1.69 +/- 0.37 ng/mL, p = 0.056). The mean chemerin concentrations were significantly elevated in the obese PCOS group compared with the obese control subjects (8.98 +/- 1.45 ng/mL versus 7.02 +/- 0.67 ng/mL, p = 0.000) and the nonobese PCOS group compared with the obese control subjects (6.57 +/- 1.17 ng/mL versus 7.02 +/- 0.67 ng/mL, p = 0.000). In conclusion, fat mass seems to be the main determinant factor of increased chemerin and decreased omentin in women with PCOS. | en_US |
dc.description.sponsorship | Namik Kemal UniversityNamik Kemal University | en_US |
dc.description.sponsorship | The contribution of all authors and project partners is acknowledged, along with the support of Namik Kemal University. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Taylor & Francis Ltd | en_US |
dc.identifier.doi | 10.3109/09513590.2014.888412 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Androgen | en_US |
dc.subject | chemerin | en_US |
dc.subject | insulin resistance | en_US |
dc.subject | omentin | en_US |
dc.subject | polycystic ovary syndrome | en_US |
dc.subject | Impaired Glucose-Tolerance | en_US |
dc.subject | Insulin-Resistance | en_US |
dc.subject | Metabolic Syndrome | en_US |
dc.subject | Adipose-Tissue | en_US |
dc.subject | Weight-Loss | en_US |
dc.subject | Prevalence | en_US |
dc.subject | Sensitivity | en_US |
dc.subject | Adiponectin | en_US |
dc.subject | Predictors | en_US |
dc.subject | Secretion | en_US |
dc.title | Omentin and chemerin and their association with obesity in women with polycystic ovary syndrome | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Gynecological Endocrinology | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.identifier.volume | 30 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 419 | en_US |
dc.identifier.endpage | 422 | en_US |
dc.institutionauthor | Güzel, Eda Çelik | |
dc.institutionauthor | Çelik, Cem | |
dc.institutionauthor | Abalı, Remzi | |
dc.institutionauthor | Guzel, Murat | |
dc.institutionauthor | Yilmaz, Murat | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 42661653300 | |
dc.authorscopusid | 24075279000 | |
dc.authorscopusid | 6506061779 | |
dc.authorscopusid | 55481926000 | |
dc.authorscopusid | 55597937800 | |
dc.authorscopusid | 56354902200 | |
dc.authorscopusid | 57197051921 | |
dc.identifier.wos | WOS:000336790400005 | en_US |
dc.identifier.scopus | 2-s2.0-84901217478 | en_US |
dc.identifier.pmid | 24524360 | en_US |