dc.contributor.author | Tülübaş, Feti | |
dc.contributor.author | Oran, Mustafa | |
dc.contributor.author | Mete, Rafet | |
dc.contributor.author | Turan, Filiz | |
dc.contributor.author | Yılmaz, Ahsen | |
dc.contributor.author | Yıldız, Zeynep Deniz | |
dc.contributor.author | Gürel, Ahmet | |
dc.date.accessioned | 2022-05-11T14:09:59Z | |
dc.date.available | 2022-05-11T14:09:59Z | |
dc.date.issued | 2014 | |
dc.identifier.issn | 1300-0144 | |
dc.identifier.issn | 1303-6165 | |
dc.identifier.uri | https://doi.org/10.3906/sag-1302-90 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5236 | |
dc.description.abstract | Aim: Irritable bowel syndrome (IBS), a functional disorder of the bowel, has been thought to result from immune activation. The aim of this study was to evaluate macrophage migration inhibitory factor (MMIF) and monocyte chemotactic protein-1 (MCP-1) levels in IBS patients. Materials and methods: We enrolled 30 IBS patients and 30 healthy controls. The MMIF and MCP-1 levels of all patients and controls were detected using commercial enzyme-linked immunosorbent assay kits. Results: Serum MMIF and MCP-1 levels were markedly higher in IBS patients than in controls. White blood cell, neutrophil, lymphocyte, monocyte, eosinophil, and basophil counts did not differ significantly between groups. Conclusion: These results show that alterations in MMIF and MCP-1 affect the proinflammatory process. They also suggest that MMIF and MCP-1 may play a substantial role in IBS. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Tubitak Scientific & Technical Research Council Turkey | en_US |
dc.identifier.doi | 10.3906/sag-1302-90 | |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Irritable bowel syndrome | en_US |
dc.subject | macrophage migration inhibitory factor | en_US |
dc.subject | monocyte chemotactic protein | en_US |
dc.subject | inflammation | en_US |
dc.subject | Dendritic Cells | en_US |
dc.subject | Ulcerative-Colitis | en_US |
dc.subject | Cytokine | en_US |
dc.subject | Expression | en_US |
dc.subject | Responses | en_US |
dc.subject | Mif | en_US |
dc.subject | Angiogenesis | en_US |
dc.subject | Growth | en_US |
dc.title | Investigation of serum macrophage migration inhibitor factor and monocyte chemotactic protein-1 levels in irritable bowel syndrome | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Turkish Journal of Medical Sciences | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Biyokimya Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalı | en_US |
dc.department | Fakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Anesteziyoloji ve Reanimasyon Ana Bilim Dalı | en_US |
dc.authorid | 0000-0002-2270-2965 | |
dc.identifier.volume | 44 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.startpage | 967 | en_US |
dc.identifier.endpage | 971 | en_US |
dc.institutionauthor | Tülübaş, Feti | |
dc.institutionauthor | Oran, Mustafa | |
dc.institutionauthor | Mete, Rafet | |
dc.institutionauthor | Turan, Filiz | |
dc.institutionauthor | Yılmaz, Ahsen | |
dc.institutionauthor | Yıldız, Zeynep Deniz | |
dc.institutionauthor | Gürel, Ahmet | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 8514414100 | |
dc.authorscopusid | 55881189500 | |
dc.authorscopusid | 36608599700 | |
dc.authorscopusid | 56388498400 | |
dc.authorscopusid | 55858591400 | |
dc.authorscopusid | 25625782200 | |
dc.authorscopusid | 36866111300 | |
dc.authorwosid | Yilmaz, Ahsen/ABB-1083-2021 | |
dc.identifier.wos | WOS:000344155900009 | en_US |
dc.identifier.scopus | 2-s2.0-84908066326 | en_US |
dc.identifier.pmid | 25552148 | en_US |