Konu "P53" için Tıp Fakültesi Koleksiyonu listeleme
Toplam kayıt 6, listelenen: 1-6
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Cryopreservation of adenovirus-transfected dendritic cells (DCs) for clinical use
(Elsevier Science Bv, 2012)In this study, we examined the effects of cryoprotectant, freezing and thawing, and adenovirus (Adv) transduction on the viability, transgene expression, phenotype, and function of human dendritic cells (DCs). DCs were ... -
Histopathological and molecular findings in 98 cases of endometrial carcinoma: MMR, p53 and next generation sequencing
(Elsevier GmbH, 2023)Gynecological malignancies arise from hereditary and somatic mutations, transcriptional aberrations, and genomic alterations influenced by epigenetic factors. This study aims to identify the mutations and their frequency ... -
miR-320a promotes p53-dependent apoptosis of prostate cancer cells by negatively regulating TP73-AS1 in vitro
(Academic Press Inc Elsevier Science, 2022)TP73 antisense RNA 1 (TP73-AS1) is an oncogenic long non-coding RNA that is activated in several types of cancers. It has been shown that the activity of TP73-AS1 is controlled by several miRNAs, but post -transcriptional ... -
Relationship of PCNA, C-erbB2 and CD44s expression with tumor grade and stage in urothelial carcinomas of the bladder
(E-Century Publishing Corp, 2014)In the present study, the intention was to reveal the relationship of histological grade and stage with c-erbB2, CD44s, and PCNA immunoreactivity in bladder urothelial carcinomas (UC). In our study, we evaluated 46 items ... -
Unraveling the molecular mechanisms behind the metabolic basis of sporadic alzheimer's disease
(IOS Press, 2009)Peripheral insulin resistance is associated with hyperinsulinemia, which may be associated with brain insulin deficiency that is characteristic of sporadic Alzheimer's disease (sAD). Oxidative insult, which is the result ... -
Variant Analysis of the Sirtuin (SIRT1) Gene in Multiple Sclerosis
(Kuwait Medical Assoc, 2013)Objective: Multiple sclerosis (MS) is an inflammatory demyelinating disease affecting the central nervous system. Although the exact pathogenesis of MS is unknown, it is generally considered to be an autoimmune disease, ...