The relationship between intracoronary thrombus burden and atherogenic index in patients with ST-elevation myocardial infarction

Abstract

- OBJECTIVE: Increased coro-nary thrombus load is a strong predictor of ad-verse cardiovascular (CV) outcomes. Identifying predictors of intracoronary thrombus burden may contribute to the management of ST -seg-ment elevation myocardial infarction (STEMI). We aimed at evaluating the relationship between the atherogenic index (ATI) and coronary throm-bus burden in patients presenting with STEMI. PATIENTS AND METHODS: 139 patients who presented with STEMI and underwent prima-ry percutaneous coronary intervention were in-cluded in this study. Angiographic thrombus burden was classified as previously defined in the myocardial infarction (TIMI) study group. RESULTS: The patients were divided into two groups as those with high and low thrombus load. Independent predictors of high thrombus burden were ATI (OR: 4.23, 95% CI: 2.38-7.5; p < 0.001), serum creatinine level (OR: 17.4, 95% CI: 3.03-101.4; p=0.001) and non-LAD involve-ment (OR: 0.363, 95% CI: 0.14-0.92; p=0.034). The association of ATI with thrombus load was independent from HDL and TGL levels. CONCLUSIONS: The atherogenic index can be used as a reliable marker for increased coro-nary thrombus burden, which is associated with adverse CV outcomes.