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Toplam kayıt 61, listelenen: 1-10
MİTOKONDRİ KONTROLLÜ APOPTOZDA SİTOKROM C SALINMASININ MATEMATİKSEL MODELLEMESİ
(Namık Kemal Üniversitesi, 2017)
Apoptoz çok hücreli bir organizmadaki hücrelerin programlı ölüm sürecidir. Mitokondri kontrollü apoptozun gerçekleşmesinde rol oynayan önemli olaylardan biri sitokrom c ve kardiyolipinin etkileşimidir. Sitokrom c mitokondri ...
Effect of hesperetin on systemic inflammation and hepatic injury after blunt chest trauma in rats
(Taylor and Francis Ltd, 2020)
We investigated the protective effect of hesperetin on hepatic damage after blunt chest trauma in rats using histological and biochemical methods. We used 18 adult male rats in three groups of six: control, chest trauma ...
Piperlongumine increases the apoptotic effect of doxorubicin and paclitaxel in a cervical cancer cell line
(Wolters Kluwer Medknow Publications, 2020)
Objective: Piperlongumine (PL) is an alkaloid derived from the edible pepper (Piper longum L) and it has been described to have various biologic activities including anticancer effects. Our aim in this study was to assess ...
Effects of combined administration of doxorubicin and chloroquine on lung pathology in mice with solid Ehrlich ascites carcinoma
(Taylor & Francis Ltd, 2022)
Combined use of a chemotherapeutic agent and an autophagy inhibitor is a novel cancer treatment strategy. We investigated the effects of chloroquine (CQ) on lung pathology caused by both solid Ehrlich ascites carcinoma ...
Long noncoding RNA ERICD interacts with ARID3A via E2F1 and regulates migration and proliferation of osteosarcoma cells
(Blackwell Publishing Ltd, 2020)
Long noncoding RNA (lncRNA) dysregulation is known to be taking part in majority of cancers, including osteosarcoma. In one of our previous studies, we showed that lncRNA MEG3 is being regulated by microRNA-664a (miR-664a) ...
Quercetin ameliorates methotrexate-induced renal damage, apoptosis and oxidative stress in rats
(Taylor & Francis Ltd, 2015)
Background: In the present study, the protective and therapeutic effects of quercetin (QE) on renal injury induced by methotrexate (MTX) have been examined. Materials and methods: A total of 24 male rats were divided into ...
Gastroprotective effect of apricot kernel oil in ethanol-induced gastric mucosal injury in rats
(Taylor & Francis Ltd, 2018)
We investigated the gastroprotective effect of apricot kernel oil on ethanol induced gastric ulcer in rats. Male Wistar albino rats were divided into control, ethanol and apricot kernel oil + ethanol groups. The fatty acid ...
Is it Possible to Treat Osteosarcoma Using Oligonucleotides Confined into Controlled Release Drug Delivery Systems?
(Bentham Science Publ Ltd, 2017)
Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
(Turkish Neurosurgical Soc, 2019)
AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
Decreased ovarian reserve in female Sprague-Dawley rats induced by isotretinoin (retinoic acid) exposure
(Elsevier Sci Ltd, 2013)
Isotretinoin is a retinoid widely used for the treatment of severe nodulocystic acne. Although it has broad side effects, there is no well-designed study about its effects on the ovary. This study investigated possible ...