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Toplam kayıt 13, listelenen: 1-10
Is it Possible to Treat Osteosarcoma Using Oligonucleotides Confined into Controlled Release Drug Delivery Systems?
(Bentham Science Publ Ltd, 2017)
Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ...
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
(Turkish Neurosurgical Soc, 2019)
AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...
Decreased ovarian reserve in female Sprague-Dawley rats induced by isotretinoin (retinoic acid) exposure
(Elsevier Sci Ltd, 2013)
Isotretinoin is a retinoid widely used for the treatment of severe nodulocystic acne. Although it has broad side effects, there is no well-designed study about its effects on the ovary. This study investigated possible ...
Thymoquinone Ameliorates Cadmium-Induced Nephrotoxicity, Apoptosis, and Oxidative Stress in Rats is Based on its Anti-Apoptotic and Anti-Oxidant Properties
(Humana Press Inc, 2016)
Cadmium (Cd), an environmental and industrial pollutant, generates free radicals responsible for oxidative stress. Cd can also lead to various renal toxic damage such as the proximal tubules and glomerulus dysfunction. ...
The effects of isotretinoin on the ovarian reserve of females with acne
(Informa Healthcare, 2014)
There are some side effects of isotretinoin in many organs. However, a study investigating the effects of isotretinoin on the human ovarian reserve has not been reported previously. The study was conducted to investigate ...
Effects of Laminar Flow Ultraviolet Sterilization Protocol on Cryptosporidium parvum Oocysts and Determination of These Effects with Vital Dyes
(Kafkas Univ, Veteriner Fakultesi Dergisi, 2011)
Cryptosporidiosis is a globally widespread protozoan disease with zoonotic character. Protection and control bear great importance for combating the disease that may cause serious economic losses. At this point, UV ...
Beneficial Effects of Quercetin on the Zone of Stasis in an Experimental Burn Model
(Aves, 2018)
Objective: In burn injury, the zone of stasis determines the width and depth of the necrosis. Our aim is to show the effectiveness of quercetin on the viability within the zone of stasis in burns of rats. Materials and ...
New Bioflavonoids from Solanum nigrum L. by Anticholinesterase and Anti-tyrosinase Activities-guided Fractionation
(Acg Publications, 2017)
Two new biflavonoids, (8-hydroxy-3'-beta-D-galactosyl-isoflavone)-2'-8'''-(4'''-hydroxy-flavone)biflavone (2); 2', 3', 5-trihydroxy-5 ''-methoxy-3 ''-O-a-glucosyl-3-4'''-O-biflavone (3) and along with apigenin (1) and ...
Dual Suppressive Effect of miR-34a on the FOXM1/eEF2-Kinase Axis Regulates Triple-Negative Breast Cancer Growth and Invasion
(Amer Assoc Cancer Research, 2018)
Purpose: Recent studies indicated that dysregulation of noncoding KNAs (ncRNA) such as miRNAs is involved in pathogenesis of various human cancers. However, the molecular mechanisms underlying miR-34a are not fully understood ...
The effects of hyperbaric oxygen application against cholestatic oxidative stress and hepatic damage after bile duct ligation in rats
(Academic Press Inc Elsevier Science, 2013)
Background: The aim of this study was to evaluate the preventive and therapeutic potential of hyperbaric oxygen therapy (HBO) on the liver tissue against bile duct ligation (BDL)-induced oxidative damage and fibrosis in ...