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Toplam kayıt 11501, listelenen: 7476-7495
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Novel inhibitors of eukaryotic elongation factor 2 kinase: in silico, synthesis and in vitro studies
(Academic Press Inc., 2021)Eukaryotic elongation factor 2 kinase (eEF2K) is an unusual alpha kinase whose expression is highly upregulated in various cancers and contributes to tumor growth, metastasis, and progression. More importantly, eEF2K ... -
A novel label free immunosensor based on single-use ITO-PET electrodes for detection MAGE1 protein
(Elsevier Science Sa, 2017)This study is aimed to design a label free biosensor based on transparent ITO-PET (Indium tin oxide-polyethylene terephthalate) electrode to determine MAGE1 protein. Firstly, indium tin oxide (ITO) electrodes were modified ... -
A novel measure to analyze protein structures: Aspect ratio in protein alpha shapes
(John Wiley and Sons Inc, 2021)Proteins' three-dimensional (3D) structures are analyzed traditionally using geometric descriptors such as torsional angles and inter-atomic distances. In this study a measure that is borrowed from computational geometry, ... -
Novel membranes regenerated from blends of cellulose/gluten using ethylenediamine/potassium thiocyanate solvent system
(Tech Science Press, 2019)Current industrial methods for dissolution of cellulose in making regenerated cellulose products are relatively expensive, toxic and dangerous and have environmental problems coming with the hazard chemical wastes. To solve ... -
A novel method for discrimination of beef and horsemeat using Raman spectroscopy
(Elsevier Sci Ltd, 2014)A new approach, based on the usage of Raman spectroscopy in combination with chemometrics, was developed for the rapid determination of beef adulteration with horsemeat. The data mining process of collected Raman spectra ... -
A Novel MIMO Antenna Design with AMC Reflector
(IEEE, 2017)We propose a low-cost, dual band (2.4-5.2 GHz) and dual band (2.4-5.8 GHz) MIMO antennas by using two identical T shaped antenna with high isolation. MIMO is a technique that is used a multiple number of antennas as a ... -
A novel missense mutation, p.(R102W) in WNT7A causes Al-Awadi Raas-Rothschild syndrome in a fetus
(Elsevier Science Bv, 2016)Al-Awadi-Raas-Rothschild syndrome (AARRS) is a rare autosomal recessive disorder which consists of severe malformations of the upper and lower limbs, abnormal genitalia and underdeveloped pelvis. Here, we present a fetus ... -
A Novel Molecule: 1-(2,6 Dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium Chloride and its Interaction with DNA
(Wiley-V C H Verlag Gmbh, 2021)Herein, a novel pyridine derivative, 1-(2,6 dichlorobenzyl)-4-(2-(2-4-hydroxybenzylidene)hydrazinyl)pyridinium chloride (DHPC), was synthesized as a candidate drug molecule. Interaction of DHPC with DNA was used to explore ... -
A Novel Mutation in the MC2R Gene Causing Familial Glucocorticoid Deficiency Type 1
(Karger, 2011)Familial glucocorticoid deficiency (FGD) or hereditary unresponsiveness to adrenocorticotropin (ACTH) is an autosomal recessive disorder characterized by isolated glucocorticoid deficiency associated with normal mineralocorticoid ... -
A Novel Mutation in the Promoter Region of the -Globin Gene: HBB: c.-127G > C
(Taylor & Francis Ltd, 2016)Novel -globin gene mutations are still occasionally being reported, especially when evaluating milder phenotypes. We report here a novel putative mutation in the promoter region of the -globin gene and assess its clinical ... -
Novel pathway for the synthesis of 20-deethyltubifolidine
(Syscom 18 SRL, 2020)A new and well planned approach has been accomplished for the total synthesis of 20-Deethyltubifolidine, which is effective for biological properties and fascinating molecules. This product embodies the ABCDE-ring system ... -
A Novel Practical Trocar Placement Technique for Extraperitoneal Laparoscopic and Robotic-Assisted Laparoscopic Radical Prostatectomy in Patients with Lower Midline Abdominal Incisions
(Mary Ann Liebert, Inc, 2014)Objective: To describe a novel practical technique for trocar placement in extraperitoneal laparoscopic radical prostatectomy (eLRP) and robotic-assisted laparoscopic radical prostatectomy (eRALP) in patients who had lower ... -
A novel rhabdovirus, related to Merida virus, in field-collected mosquitoes from Anatolia and Thrace
(Springer Wien, 2017)Next-generation sequencing technologies have significantly facilitated the discovery of novel viruses, and metagenomic surveillance of arthropods has enabled exploration of the diversity of novel or known viral agents. We ... -
A novel silanization agent based single used biosensing system: Detection of C-reactive protein as a potential Alzheimer's disease blood biomarker
(Elsevier Science Bv, 2018)This paper illustrates a new and sensitive electrochemical immunosensor for the analysis of C-reactive protein. Indium Tin Oxide (ITO) disposable sheets were modified by using 3-cyanopropyltrimethoxysilane (CPTMS) ... -
Novel Single Nucleotide Polymorphisms of Lysozyme (C-Type) Gene in Donkey (Equus Asinus) Populations in Marmara Province of Turkey
(2020)The major antimicrobial proteins in donkey milk are lysozyme, lactoferrin, lactoperoxidase andimmunoglobulins. Lysozyme has an important role in the host defense by way it inhibits the pathogenic bacteria. The aim of this ... -
Novel SNARE Complex Polymorphisms Associated with Multiple Sclerosis: Signs of Synaptopathy in Multiple Sclerosis
(2019)Background: It is well known that axonal degeneration plays a role in disability in patients with multiple sclerosis, and synaptopathy has recently become an important issue.Aims: To investigate the possible roles of ... -
A novel synthesis of (3,6-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-9-(4-vinylbenzyl)-9H-carbazole), alternating polymer formation, characterization, and capacitance measurements
(Springer, 2013)In this work, (3,6-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-9-(4-vinylbenzyl)-9H-carbazole) (EDOTVBCz) comonomer was chemically synthesized and characterized by Fourier transform infrared (FTIR), proton nuclear magnetic ... -
A novel synthesis of 3,6-bis(2,3-dihydrothieno[3,4-b][1,4]dioxin-5-yl)-9-tosyl-9H-carbazole
(Ovidius Univ Press, 2012)3,6-bis(2,3-dihydrothieno [3,4-b][1,4]dioxin-5-yl)-9-tosyl-9H-carbazole (EDOTTsCz) was synthesized and electrochemically polymerized on glassy carbon electrode (GCE) in 0.1 M tetrabutyl ammonium tetrafluoroborate ... -
A novel synthesis of 4-toluene 9H-carbazole-9-carbodithioate, electropolymerization and impedance study
(Budapest Univ Technol & Econ, 2014)A novel synthesis of 4-toluene 9H-carbazole-9-carbodithioate (TCzC) was chemically synthesized and characterized by Fourier Transform Infrared (FTIR), proton nuclear magnetic resonance (H-1-NMR), and carbon nuclear magnetic ... -
A novel synthesis of octahydropyrido[3,2-c]carbazole framework of aspidospermidine alkaloids and a combined computational, FT-IR, NMR, NBO, NLO, FMO, MEP study of the cis-4a-Ethyl-1(2hydroxyethyl)-2,3,4,4a,5,6,7,11c-octahydro-1H-pyrido[3,2-c] carbazole
(Elsevier, 2018)In this study, we performed a novel synthesis of the octahydropyrido[3,2-c]carbazole derivative 6 from 1 in five steps with a 34% overall yield. We also developed a unique compound 2 by a cyclization reaction from the ...
