dc.contributor.author | Çağlar, Kübra | |
dc.contributor.author | Kocabay, A. | |
dc.contributor.author | Taşkın, Ali Cihan | |
dc.contributor.author | Arat, Sezen | |
dc.date.accessioned | 2022-05-11T14:10:24Z | |
dc.date.available | 2022-05-11T14:10:24Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0143-2044 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5390 | |
dc.description.abstract | BACKGROUND: Melatonin is an endocrine hormone secreted from the pineal gland located outside the blood-brain barrier. OBJECTIVE: In this study, in vitro propagated eight-cell mouse embryos were vitrified by the Solid Surface Vitrification (SSV) method and after thawing, their in vitro development and embryo qualities in melatonin added media were investigated. METHODS: Pronuclear stage embryos obtained from super ovulated B6CBAF1/J strain mice, were cultured until the eight-cell stage. Then these eight-cell embryos were vitrified by the SSV method and after thawing, cultured in melatonin added media at 37°C and 5 %CO2 conditions until the blastocyst stage. RESULT: In the experimental period, in vitro embryo development rates of the control, SSV and +10-12 M melatonin groups were observed as 97%, 86% and 93%, respectively. CONCLUSION: Our results indicated that melatonin addition slightly increased the development rates and total cell numbers of embryos vitrified by the SSV method. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | NLM (Medline) | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | melatonin | en_US |
dc.subject | animal | en_US |
dc.subject | blastocyst | en_US |
dc.subject | cryopreservation | en_US |
dc.subject | mammalian embryo | en_US |
dc.subject | mouse | en_US |
dc.subject | vitrification | en_US |
dc.subject | Animals | en_US |
dc.subject | Blastocyst | en_US |
dc.subject | Cryopreservation | en_US |
dc.subject | Embryo, Mammalian | en_US |
dc.subject | Melatonin | en_US |
dc.subject | Mice | en_US |
dc.subject | Vitrification | en_US |
dc.title | Treatment with Melatonin Enhances the Embryo Quality and the Development of Vitrified/warmed Eight Cell Mouse Embryos by Solid Surface Vitrification (SSV) | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Cryo letters | en_US |
dc.department | Fakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü | en_US |
dc.department | Enstitüler, Fen Bilimleri Enstitüsü, Tarımsal Biyoteknoloji Ana Bilim Dalı | en_US |
dc.identifier.volume | 41 | en_US |
dc.identifier.issue | 2 | en_US |
dc.identifier.startpage | 62 | en_US |
dc.identifier.endpage | 67 | en_US |
dc.institutionauthor | Çağlar, Kübra | |
dc.institutionauthor | Arat, Sezen | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 57223956195 | |
dc.authorscopusid | 57209266981 | |
dc.authorscopusid | 41862429400 | |
dc.authorscopusid | 6603553213 | |
dc.identifier.scopus | 2-s2.0-85106554057 | en_US |
dc.identifier.pmid | 33988655 | en_US |