dc.contributor.author | Özcan Gökçek, Emel | |
dc.contributor.author | Işık, Raziye | |
dc.date.accessioned | 2022-05-11T14:07:11Z | |
dc.date.available | 2022-05-11T14:07:11Z | |
dc.date.issued | 2020 | |
dc.identifier.issn | 0920-1742 | |
dc.identifier.uri | https://doi.org/10.1007/s10695-020-00779-8 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11776/5001 | |
dc.description.abstract | The IGF-I is a significant peptide hormone to cell growth, development, reproduction, and metabolism of teleost fish. This study was conducted to investigate the IGF-I gene polymorphism and to reveal the association between the genotypes of IGF-I gene and growth traits in 80 harvest size European sea bass (Dicentrarchus labrax, L.) reared in İzmir region of Turkey. The 821 bp long exon 1 and 5’ UTR regions of IGF-I gene were amplified, and PCR products were analyzed via DNA sequencing method. Two novel single nucleotide polymorphisms (SNPs) such as g.46672A > G and g.46749C > T in the 5’ UTR region of IGF-I gene in the European sea bass were detected for the first time with this study. Associations between the genotypes of IGF-I g.46749C > T locus and body weight were found statistically significant (p < 0.05). The genotypes of IGF-I g.46749C > T and g.46672A > G loci were found significantly associated with total length (p < 0.05). However, both loci did not show significant associations with body width. The studied gene region sequences were entered to NCBI GenBank database with the accession numbers: MK621680-MK621682. Thus, these polymorphisms have a significant effect on the body weight and total length which could be useful for sea bass selection and breeding for marker-assisted selection (MAS) program. © 2020, Springer Nature B.V. | en_US |
dc.language.iso | eng | en_US |
dc.publisher | Springer | en_US |
dc.identifier.doi | 10.1007/s10695-020-00779-8 | |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | DNA sequencing | en_US |
dc.subject | European sea bass | en_US |
dc.subject | IGF-I gene | en_US |
dc.subject | Polymorphism | en_US |
dc.subject | fish protein | en_US |
dc.subject | somatomedin C | en_US |
dc.subject | animal | en_US |
dc.subject | bass | en_US |
dc.subject | DNA sequence | en_US |
dc.subject | genetics | en_US |
dc.subject | genotype | en_US |
dc.subject | growth, development and aging | en_US |
dc.subject | male | en_US |
dc.subject | single nucleotide polymorphism | en_US |
dc.subject | turkey (bird) | en_US |
dc.subject | Animals | en_US |
dc.subject | Bass | en_US |
dc.subject | Fish Proteins | en_US |
dc.subject | Genotype | en_US |
dc.subject | Insulin-Like Growth Factor I | en_US |
dc.subject | Male | en_US |
dc.subject | Polymorphism, Single Nucleotide | en_US |
dc.subject | Sequence Analysis, DNA | en_US |
dc.subject | Turkey | en_US |
dc.title | Associations between genetic variants of the insulin-like growth factor I (IGF-I) gene and growth traits in European sea bass (Dicentrarchus labrax, L.) | en_US |
dc.type | article | en_US |
dc.relation.ispartof | Fish Physiology and Biochemistry | en_US |
dc.department | Fakülteler, Ziraat Fakültesi, Tarımsal Biyoteknoloji Bölümü | en_US |
dc.identifier.volume | 46 | en_US |
dc.identifier.issue | 3 | en_US |
dc.identifier.startpage | 1131 | en_US |
dc.identifier.endpage | 1138 | en_US |
dc.institutionauthor | Işık, Raziye | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.authorscopusid | 55907746500 | |
dc.authorscopusid | 57200696504 | |
dc.identifier.wos | WOS:000518425400001 | en_US |
dc.identifier.scopus | 2-s2.0-85081609857 | en_US |
dc.identifier.pmid | 32140978 | en_US |