Yazar "Karaarslan, Numan" için listeleme
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Is it Possible to Treat Osteosarcoma Using Oligonucleotides Confined into Controlled Release Drug Delivery Systems?
Topuk, Savaş; Akyuva, Yener; Karaarslan, Numan; Mutlu, Çağrı A.; Yılmaz, İbrahim; İşyar, Mehmet; Mahiroğulları, Mahir (Bentham Science Publ Ltd, 2017)Purpose: The present study aimed to analyze the researches that are at the experimental phase concerning osteosarcoma treatment. The researches included drug delivery systems which allow controlled release and imbue small ... -
Ligamentum Flavumu İnvaze Eden Primer Servikal Osteosarkom: Olgu Sunumu
Karaarslan, Numan; Çalışkan, Tezcan; Şimşek, Abdullah Talha (Namık Kemal Üniversitesi, 2017)Primer servikal spinal osteosarkomlar oldukça nadir görülen patolojiler olup, nadir olarak ligamentum flavum invazyonu yapmaktadırlar. Servikal bölgenin kompleks anatomik yapısı nedeni ile tümöral dokunun cerrahi rezeksiyon ... -
Lomber spinal stenoz olgularının cerrahi tedavisinde uygulanan rijid pedikül-rod sistemleri ve dinamik polyetheretherketone (peek) rod sistemlerinin postoperatif komşu segment dejenerasyon süreçleri üzerine etkilerinin retrospektif olarak değerlendirilerek karşılaştırılması
Potoğlu, Bilgehan (Tekirdağ Namık Kemal Üniversitesi, 2021)Lomber spinal stenoz (LSS), özellikle 65 yaş üstü olgularda kalça ve alt ektsremitelerde ortaya çıkan ağrının ve fonksiyonel kaybın en sık nedenidir. Yaşam kalitesini önemli ölçüde etkileyen bu patolojiler ülke ekonomilerine ... -
Lumbar spinal angiolipoma with expanding left neural foramen mimicking lumbar schwannoma; case report and review of the literature
Akyuva, Yener; Gönültaş, Aylin; Karaarslan, Numan; Gülçiftçi Dağcı, Zeliha; Sağlık, Semih; İşyar, Mehmet; Mahiroğulları, Mahir (Bentham Science Publishers B.V., 2017)Aim: To describe a patient with lumbar angiolipoma mimicking schwannoma in the posterolateral side of the spinal canal with expansion of the left lumbar foramen and to discuss the clinical, radiologic, and surgical features ... -
Pharmaco-molecular assessment of the effects of anandamide and its antagonists on hippocampal tissue in Wistar albino rats
Yılmaz, İbrahim; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi (Verduci Publisher, 2020)OBJECTIVE: The members of the matrix metalloproteinase (MMP) family and cannabinoids (CBs) are reportedly associated with hippocampus-dependent memory functions. However, the effects of endogenously formed CBs on hippocampal ... -
Postoperative analgesic effect of bupivacaine infiltration following lumbar disc surgery
Objectives: Effectiveness of 0.5% bupivacaine administered onto dura, under lumbar superficial fascia andsubcutaneous tissue on postoperative pain control was analyzed in patients undergoing lumbar microdiscectomy.Methods: ... -
Practical Performance of Hippocampal Tissue Resection in Rats in Pharmacomolecular Research
Yılmaz, İbrahim; Karaarslan, Numan; Özbek, Hanefi (Turkish Neurosurgical Soc, 2021)AIM: To explain how to resect hippocampal tissue in rats used as live mammalian subjects for the resection of fresh cerebral tissue in laboratories. MATERIAL and METHODS: Adult male Wistar-Albino rats (n=50) were used for ... -
Pregabalin treatment for neuropathic pain may damage intervertebral disc tissue
Karaarslan, Numan; Yılmaz, İbrahim; Şirin, Duygu Yaşar; Özbek, Hanefi; Kaplan, Necati; Kaya, Yasin Emre; Ateş, Özkan (Spandidos Publ Ltd, 2018)The aim of the present study was to determine whether pharmaceutical preparations with pregabalin (PGB) as an active ingredient, which are widely prescribed by clinicians, exert toxic effects on human primary nucleus ... -
Remote Cerebellar Haemorrhage after Burr Hole Drainage of Chronic Subdural Haematoma: A Case Report
Gürbüz, Mehmet Sabri; Karaarslan, Numan; Gök, Sevki; Soyalp, Celaleddin (Premchand Shantidevi Research Foundation, 2016)Remote cerebellar haemorrhage (RCH) is an unusual complication of supratentorial neurosurgical procedures. Even the rarer is cerebellar haemorrhage occurring after supratentorial burr hole drainage of Chronic Subdural ... -
Remote Cerebellar Haemorrhage Occurring after Transcranial Pituitary Surgery
Karaarslan, Numan; Gürbüz, Mehmet Sabri; Çalışkan, Tezcan; Tunckale, Tamer (Premchand Shantidevi Research Foundation, 2017)Post supratentorial and spinal surgeries, in rare cases, Remote Cerebellar Haemorrhage (RCH) develops as a complication. Although the exact aetiology of RCH remains uncertain, excessive drainage of the Cerebrospinal Fluid ... -
Sequestrectomy or microdiscectomy in patients with lumbar disc herniation
Somay, Hakan; Karaarslan, Numan (2019)Aim: Which microsurgical method can provide better outcomes for patients with lumbar disc herniation (LDH) is still unclear in the literature. In the present study, the aim was to retrospectively examine the efficacy of ... -
Severe head trauma in children: Analysis of 68 cases in light of current guidelines
Gürbüz, Mehmet Sabri; Duyu, Muhterem; Gezen, Ahmet Ferruh; Canızcı Erdemli, Pınar; Boşnak, Ercan; Elias, Çimen; Karaarslan, Numan (2020)Aim: To assess the characteristics of severe head trauma in the pediatric age group and to analyze its results under the currentguideline.Material and Methods: Eighty pediatric patients (<18 years) admitted to our hospital ... -
Spinal Cerrahide Gelecek Vaat Eden Moleküler Gelişmeler
Amaç: Bu çalışmada, dünya genelinde yapılan çalışmalariçerisinde, omurga patolojisinin giderilmesinde araştırılan,moleküler düzeyde gerçekleştirilen hücresel bazlı hedeftedavilerin, sistematik olarak incelenip, konu ... -
Spontaneous Subdural Haematoma Developing Secondary to Arachnoid Cyst Rupture
Yüksel, Mehmet Onur; Gürbüz, Mehmet Sabri; Şenol, Mehmet; Karaarslan, Numan (Premchand Shantidevi Research Foundation, 2016)Arachnoid cysts are congenital, benign, non-neoplastic, extra-axial intra-arachnoidal lesions. Arachnoid cysts rarely become symptomatic, with bleeding. Intracranial haemorrhage as a complication of arachnoid cyst is a ... -
A Study of the Effects of Metformin, a Biguanide Derivative, on Annulus Fibrosus and Nucleus Pulposus Cells
Kaya, Yasin Emre; Karaarslan, Numan; Yılmaz, İbrahim; Şirin, Duygu Yaşar; Akalan, Hande; Özbek, Hanefi (Turkish Neurosurgical Soc, 2020)AIM: To investigate the effects of metformin, a drug used widely for the treatment of type 2 diabetes mellitus, on human primary cell cultures prepared from uninjured segment of disc material intervertebral disk tissues. ... -
A study on legal and medical dimensions of radiation exposure in neurosurgery clinics in Turkish practice
Karaarslan, Abdulkadir; Kasim, F.B.H.; Karaarslan, Numan; Ateş, Özkan (Scientific Scholar, 2020)Background: In the present study, the first aim was to address the detrimental effects of the fluoroscopy procedure performed by physicians and other health-care professionals in neurosurgery clinics, then to examine ... -
A study on side effects of antibiotics used in the treatment of patients with head trauma and legal responsibility of clinicians in terms of the right to health
Karaarslan, Abdulkadir; Şimşek, Abdullah Talha; Doğan, Mustafa; Potoglu, Bilgehan; Yılmaz, İbrahim; Karaarslan, Numan (2019)Aim: Patients with head trauma are routinely, and commonly treated with prophylactic antibiotics, which may also be used for thetreatment of infection that may be developed during hospital stay. The relevant antibiotic ... -
A Study on the Effects of Direct Factor Xa Inhibitors and Direct Thrombin Inhibitors on Human Primary Chondrocyte Cultures
Kaya, Yasin Emre; Akalan, Hande; Yılmaz, İbrahim; Karaarslan, Numan; Şirin, Duygu Yaşar; Özbek, Hanefi; Ateş, Özkan (2019)Aim:This study investigates the effects of two direct factor Xa inhibitors, apixaban and rivaroxaban, and a direct thrombin inhibitor, dabigatran, on human primary chondrocytecultures.Materials and Methods:Monolayer cultured ... -
Systematic Evaluation of Desmopressin Administered to Patients with Aneurysmal Subarachnoid Hemorrhage in the Light of the Literature
Karaarslan, Numan; Yılmaz, İbrahim; Akgün, Feride Sinem; Çalışkan, Tezcan; Özbek, Hanefi; Ateş, Özkan (Turkish Neurosurgical Soc, 2020)AIM: To discuss the management of patients with the syndrome of inappropriate antidiuretic hormone secretion (SIADH) developing after subarachnoid hemorrhage, in a comparative manner in the light of the literature. MATERIAL ... -
Systematic Evaluation of Promising Clinical Trials-Gene Silencing for the Treatment of Glioblastoma
Karaarslan, Numan; Yılmaz, İbrahim; Özbek, Hanefi; Çalışkan, Tezcan; Topuk, Savas; Yasar Şirin, Duygu; Ateş, Özkan (Turkish Neurosurgical Soc, 2019)AIM: To systematically investigate the role of artificial small interfering RNA (SiRNA) molecules in glioblastoma treatment and to give a detailed overview of the literature concerning studies performed in this field ...